Hypoxia makes its mark on histones

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Comment

Paulina Strzyz. Nat Rev Mol Cell Biol. 2019 Jun.

. 2019 Jun;20(6):324-325.

doi: 10.1038/s41580-019-0122-6.

No abstract available

Comment on

Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate.
Chakraborty AA, Laukka T, Myllykoski M, Ringel AE, Booker MA, Tolstorukov MY, Meng YJ, Meier SR, Jennings RB, Creech AL, Herbert ZT, McBrayer SK, Olenchock BA, Jaffe JD, Haigis MC, Beroukhim R, Signoretti S, Koivunen P, Kaelin WG Jr. Chakraborty AA, et al. Science. 2019 Mar 15;363(6432):1217-1222. doi: 10.1126/science.aaw1026. Epub 2019 Mar 14. Science. 2019. PMID: 30872525 Free PMC article.
Hypoxia induces rapid changes to histone methylation and reprograms chromatin.
Batie M, Frost J, Frost M, Wilson JW, Schofield P, Rocha S. Batie M, et al. Science. 2019 Mar 15;363(6432):1222-1226. doi: 10.1126/science.aau5870. Epub 2019 Mar 14. Science. 2019. PMID: 30872526

1. Batie, M. et al. Hypoxia induces rapid changes to histone methylation and reprograms chromatin. Science 363, 1222–1226 (2019) - DOI
1. Chakraborty, A. A. et al. Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate. Science 363, 1217–1222 (2019) - DOI