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1 Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine (S.C.L.), Huddinge, Karolinska Institutet, Stockholm, Sweden.
2 Department of Surgical Sciences, The EpiHub, Uppsala University (S.C.L.).
3 Department of Medicine (N.D.), Huddinge, Karolinska Institutet, Stockholm, Sweden.
4 Division of Arrhythmia, Karolinska University Hospital, Stockholm, Sweden (N.D.).
5 Department of Public Health and Primary Care (A.M.M., S.B.), University of Cambridge, United Kingdom.
6 MRC Biostatistics Unit (S.B.), University of Cambridge, United Kingdom.
1 Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine (S.C.L.), Huddinge, Karolinska Institutet, Stockholm, Sweden.
2 Department of Surgical Sciences, The EpiHub, Uppsala University (S.C.L.).
3 Department of Medicine (N.D.), Huddinge, Karolinska Institutet, Stockholm, Sweden.
4 Division of Arrhythmia, Karolinska University Hospital, Stockholm, Sweden (N.D.).
5 Department of Public Health and Primary Care (A.M.M., S.B.), University of Cambridge, United Kingdom.
6 MRC Biostatistics Unit (S.B.), University of Cambridge, United Kingdom.
Associations of genetically predicted 10 beats per minute increase of resting heart rate…
Figure 1
Associations of genetically predicted 10 beats per minute increase of resting heart rate with coronary artery disease, atrial fibrillation, and ischemic stroke and its subtypes. The Mendelian randomization analyses were conducted using summarized data on coronary artery disease are from the Coronary Artery Disease consortium’s 1000 Genomes-based genome-wide association study, atrial fibrillation from the Atrial Fibrillation Consortium and ischemic stroke from the MEGASTROKE consortium. CI, confidence interval; IVW, inverse-variance weighted; OR, odds ratio.
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