Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986 Jul;204(1):180-4.
doi: 10.1007/BF00330207.

Autoregulation of the nar operon encoding nitrate reductase in Escherichia coli

V Bonnefoy, M C Pascal, J Ratouchniak, M Chippaux

Autoregulation of the nar operon encoding nitrate reductase in Escherichia coli

V Bonnefoy et al. Mol Gen Genet. 1986 Jul.

Abstract

Nitrate reductase is demonstrated to exert an autogenous control on its own synthesis. This effect requires the participation of the molybdenum cofactor. Use of strains in which the control region of the nar operon is mutated reveals two loci in this region: one, affected in strain LCB94, is common to both autoregulation and induction by nitrate while the other, mutated in strain LCB188, is specific for the induction by nitrate. It is proposed that the autogenous control prevents the unnecessary accumulation of the nitrate reductase subunits in the cytoplasm.

PubMed Disclaimer

References

    1. J Bacteriol. 1969 Mar;97(3):1374-8 - PubMed
    1. J Bacteriol. 1983 Apr;154(1):387-94 - PubMed
    1. Mol Gen Genet. 1981;181(4):535-40 - PubMed
    1. Mol Gen Genet. 1981;182(3):477-9 - PubMed
    1. J Bacteriol. 1975 Mar;121(3):1117-21 - PubMed

LinkOut - more resources