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. 2019 Mar 28;15(3):e1007600.
doi: 10.1371/journal.ppat.1007600. eCollection 2019 Mar.

Did new transmission cycles in anthropogenic, dense, host populations encourage the emergence and speciation of pathogenic Bordetella?

Kalyan K Dewan  1 , Eric T Harvill  1
Affiliations

Did new transmission cycles in anthropogenic, dense, host populations encourage the emergence and speciation of pathogenic Bordetella?

Kalyan K Dewan et al. PLoS Pathog. .
No abstract available

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Independent but interconnected life cycles of Bordetella bronchiseptica.
B. bronchiseptica (red rods) can infect a range of mammalian species as a respiratory pathogen. Alternately, it can associate with predatory amoeba to expand in numbers and disperse in the environment via their complex life cycle.
Fig 2
Fig 2. A Bordetella metacycle of transmission: The source of host-restricted species.
Schematic of a progenitor Bordetella species involved in a complex metacycle of transmission involving alternative cycles in environmental protists or animal host species. Phylogenetic relations strongly indicate that host specializations of transmission restricted species, including B. pertussis, evolved from a metacycle of transmission of a B. bronchiseptica-like ancestor. [Image by: Danielle Brittany Vanbrabrant ©2019—University of Georgia Research Foundation, Inc.].
See this image and copyright information in PMC

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