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Editorial
. 2019 Apr;69(681):166-167.
doi: 10.3399/bjgp19X701897.

Valproate and the Pregnancy Prevention Programme: exceptional circumstances

Lance V Watkins  1 , Hannah R Cock  2 , Heather Angus-Leppan  3 , Rohit Shankar  4
Affiliations
Editorial

Valproate and the Pregnancy Prevention Programme: exceptional circumstances

Lance V Watkins et al. Br J Gen Pract. 2019 Apr.
No abstract available

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References

    1. Medicines and Healthcare products Regulatory Agency Valproate use by women and girls. Guidance. MHRA. 2018 https://www.gov.uk/guidance/valproate-use-by-women-and-girls (accessed 28 Feb 2019).
    1. Hernández-Díaz S, Smith CR, Shen A, et al. Comparative safety of antiepileptic drugs during pregnancy. Neurology. 2012;78(21):1692–1699. - PubMed
    1. Vajda FJ, O’Brien TJ, Graham JE, et al. Dose dependence of fetal malformations associated with valproate. Neurology. 2013;81(11):999–1003. - PubMed
    1. Campbell E, Kennedy F, Russell A, et al. Malformation risks of antiepileptic drug monotherapies in pregnancy: updated results from the UK and Ireland Epilepsy and Pregnancy Registers. J Neurol Neurosurg Psychiatry. 2014;85(9):1029–1034. - PubMed
    1. Tomson T, Battino D, Bonizzoni E, et al. Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry. Lancet Neurol. 2018;17(6):530–538. - PubMed

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