Shear stress makes its mark on the endothelial genome
- PMID: 30924878
- PMCID: PMC6648336
- DOI: 10.1093/cvr/cvz088
Shear stress makes its mark on the endothelial genome
Figures
Comment on
-
Identification of atheroprone shear stress responsive regulatory elements in endothelial cells.Cardiovasc Res. 2019 Aug 1;115(10):1487-1499. doi: 10.1093/cvr/cvz027. Cardiovasc Res. 2019. PMID: 30785199
References
-
- Kwak BR, Bäck M, Bochaton-Piallat M-L, Caligiuri G, Daemen MJAP, Davies PF, Hoefer IE, Holvoet P, Jo H, Krams R, Lehoux S, Monaco C, Steffens S, Virmani R, Weber C, Wentzel JJ, Evans PC.. Biomechanical factors in atherosclerosis: mechanisms and clinical implications. Eur Heart J 2014;35:3013–3020. - PMC - PubMed
-
- Stone PH, Saito S, Takahashi S, Makita Y, Nakamura S, Kawasaki T, Takahashi A, Katsuki T, Nakamura S, Namiki A, Hirohata A, Matsumura T, Yamazaki S, Yokoi H, Tanaka S, Otsuji S, Yoshimachi F, Honye J, Harwood D, Reitman M, Coskun AU, Papafaklis MI, Feldman CL. PREDICTION Investigators. Prediction of progression of coronary artery disease and clinical outcomes using vascular profiling of endothelial shear stress and arterial plaque characteristics the PREDICTION Study. Circulation 2012;126:172–181. - PubMed
-
- Pedrigi RM, Poulsen CB, Mehta VV, Ramsing Holm N, Pareek N, Post AL, Kilic ID, Banya WAS, Dall’Ara G, Mattesini A, Bjørklund MM, Andersen NP, Grøndal AK, Petretto E, Foin N, Davies JE, Di Mario C, Fog Bentzon J, Erik Bøtker H, Falk E, Krams R, de Silva R.. Inducing persistent flow disturbances accelerates atherogenesis and promotes thin cap fibroatheroma development in D374Y-PCSK9 hypercholesterolemic minipigs. Circulation 2015;132:1003–1012. - PubMed
-
- Souilhol C, Harmsen MC, Evans PC, Krenning G.. Endothelial-mesenchymal transition in atherosclerosis. Cardiovasc Res 2018;114:565–577. - PubMed
-
- Tricot O, Mallat Z, Heymes C, Belmin J, Leseche G, Tedgui A.. Relation between endothelial cell apoptosis and blood flow direction in human atherosclerotic plaques. Circulation 2000;101:2450–2453. - PubMed