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Review
. 2019 May;29(2):203-213.
doi: 10.1016/j.thorsurg.2018.12.007. Epub 2019 Mar 7.

Surgical Decision Making: Thymoma and Myasthenia Gravis

Giovanni M Comacchio  1 , Giuseppe Marulli  2 , Marco Mammana  1 , Giuseppe Natale  1 , Marco Schiavon  1 , Federico Rea  3
Affiliations
Review

Surgical Decision Making: Thymoma and Myasthenia Gravis

Giovanni M Comacchio et al. Thorac Surg Clin. 2019 May.

Abstract

About 15% of patients with myasthenia gravis are affected by thymoma. Precise tumor staging is necessary to plan the appropriate operation. In early stages, complete surgical resection is the mainstay of treatment. Minimally invasive approaches can be safely performed by highly trained surgeons, and may be preferred in myasthenic patients because they can ensure optimal results from the oncological, neurologic, and surgical point of views, avoiding the complications of open approach. For advanced stage thymoma in myasthenic patients, a careful, multidisciplinary planning of the therapeutic approach must be undertaken, particularly for extended resections involving the lung and great vessels.

Keywords: Mediastinum; Myasthenia gravis; Surgery; Thymoma; Thymus.

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