Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2019 May;19(5):251.
doi: 10.1038/s41568-019-0138-4.

What's driving T cell dysfunction?

Alexandra Flemming  1
Affiliations
Comment

What's driving T cell dysfunction?

Alexandra Flemming. Nat Rev Cancer. 2019 May.
No abstract available

PubMed Disclaimer

Comment on

  • Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction.
    Liu X, Wang Y, Lu H, Li J, Yan X, Xiao M, Hao J, Alekseev A, Khong H, Chen T, Huang R, Wu J, Zhao Q, Wu Q, Xu S, Wang X, Jin W, Yu S, Wang Y, Wei L, Wang A, Zhong B, Ni L, Liu X, Nurieva R, Ye L, Tian Q, Bian XW, Dong C. Liu X, et al. Nature. 2019 Mar;567(7749):525-529. doi: 10.1038/s41586-019-0979-8. Epub 2019 Feb 27. Nature. 2019. PMID: 30814730 Free PMC article.
  • NR4A transcription factors limit CAR T cell function in solid tumours.
    Chen J, López-Moyado IF, Seo H, Lio CJ, Hempleman LJ, Sekiya T, Yoshimura A, Scott-Browne JP, Rao A. Chen J, et al. Nature. 2019 Mar;567(7749):530-534. doi: 10.1038/s41586-019-0985-x. Epub 2019 Feb 27. Nature. 2019. PMID: 30814732 Free PMC article.

MeSH terms

Substances

LinkOut - more resources