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. 2019 Jan-Mar;14(1):90-95.
doi: 10.4103/ajns.AJNS_81_17.

Magnetic Resonance Imaging-guided Stereotactic Biopsy: A Review of 83 Cases with Outcomes

Ali Akay  1 , Mete Rüksen  1 , Sertaç Islekel  1
Affiliations

Magnetic Resonance Imaging-guided Stereotactic Biopsy: A Review of 83 Cases with Outcomes

Ali Akay et al. Asian J Neurosurg. 2019 Jan-Mar.

Abstract

Background: The purpose of this study was to determine the relationship between the radiological and histopathological distribution of the cerebral lesions diagnosed with stereotactic biopsy (STB) procedure and its outcomes.

Materials and methods: In the current study, a retrospective analysis of 83 patients that underwent the STB in our clinic from January 2011 to December 2015 was made. T1-weighted contrast-enhanced cranial magnetic resonance imaging examinations were performed on patients on whom Leksell stereotactic frame system was installed. The histopathological and the radiological data derived from the STB procedure were classified.

Results: In terms of localization, glial tumor (56.6%) was the most common lesion in all regions, except for the multifocal lesions. Contrary to the common knowledge, lymphoma (14.4%) was found to be the most common lesion among multifocal lesions. The success of obtaining positive STB samples in the current series was 95.2% and the complication rate was 3.6%.

Conclusion: Had a routine computed tomography scan been performed on each patient in this series, the number of clinically insignificant small intracerebral hematomas would have probably been higher. Nevertheless, the rate of the STB sampling accuracy and the complication rate were similar to those reported in the relevant literature.

Keywords: Brain lesion; complication; histopathology; radiology; stereotactic biopsy.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
(a) Grade 4 glial tumor (glioblastoma multiforme), (b) lymphoma, (c) Grade 1 glial tumor (subependymal giant cell astrositoma)
Figure 2
Figure 2
(a) Abscess, (b) Grade 2 glial tumor (astrocytoma), (c) infarct, (d) Grade 3 glial tumor (anaplastic astrocytoma)
Figure 3
Figure 3
(a) Histiocytosis and (b) cerebritis
Figure 4
Figure 4
(a) Small round cell tumor, (b) histiocytosis, (c) metastasis
Figure 5
Figure 5
(a) Grade 4 glial tumor (glioblastoma multiforme), (b) Grade 2 glial tumor (atypical pilocytic astrocytoma), and (c) neuroepithelial cyst
See this image and copyright information in PMC

References

    1. Leksell L. A stereotaxic apparatus for intracerebral surgery. Acta Chir Scand. 1949;99:229–333.
    1. Spiegel EA, Wycis HT, Marks M, Lee AJ. Stereotaxic apparatus for operations on the human brain. Science. 1947;106:349–50. - PubMed
    1. Lacroix M, Abi-Said D, Fourney DR, Gokaslan ZL, Shi W, DeMonte F, et al. A multivariate analysis of 416 patients with glioblastoma multiforme: Prognosis, extent of resection, and survival. J Neurosurg. 2001;95:190–8. - PubMed
    1. Wood JR, Green SB, Shapiro WR. The prognostic importance of tumor size in malignant gliomas: A computed tomographic scan study by the Brain Tumor Cooperative Group. J Clin Oncol. 1988;6:338–43. - PubMed
    1. Bouvier G, Couillard P, Leger SL, Lesage J, Rotent F, Beique RA, et al. Stereotactic biopsy of cerebral space-occupying lesions. Appl Neurophysiol. 1983;46:227–30. - PubMed