Peripheral afferents and the pain experience
- PMID: 30939586
- DOI: 10.1097/j.pain.0000000000001527
Peripheral afferents and the pain experience
Comment on
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The role of afferent input in postamputation pain: a randomized, double-blind, placebo-controlled crossover study.Pain. 2019 Jul;160(7):1622-1633. doi: 10.1097/j.pain.0000000000001536. Pain. 2019. PMID: 30817438 Clinical Trial.
References
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- Black JA, Nikolajsen L, Kroner K, Jensen TS, Waxman SG. Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas. Ann Neurol 2008;64:644–53.
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- Buch NS, Ahlburg P, Haroutounian S, Andersen NT, Finnerup NB, Nikolajsen N. The role of afferent input in postamputation pain: a randomized, double-blind, placebo-controlled crossover study. PAIN 2019;160:1622–33.
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- Cao L, McDonnell A, Nitzsche A, Alexandrou A, Saintot PP, Loucif AJ, Brown AR, Young G, Mis M, Randall A, Waxman SG, Stanley P, Kirby S, Tarabar S, Gutteridge A, Butt R, McKernan RM, Whiting P, Ali Z, Bilsland J, Stevens EB. Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia. Sci Transl Med 2016;8:335ra56.
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- Cummins TR, Waxman SG. Downregulation of tetrodotoxin-resistant sodium currents and upregulation of a rapidly repriming tetrodotoxin-sensitive sodium current in small spinal sensory neurons after nerve injury. J Neurosci 1997;17:3503–14.
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- Dib-Hajj SD, Black JA, Cummins TR, Kenney AM, Kocsis JD, Waxman SG. Rescue of alpha-SNS sodium channel expression in small dorsal root ganglion neurons after axotomy by nerve growth factor in vivo. J Neurophysiol 1998;79:2668–76.
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