Reductionist thinking and animal models in neuropsychiatric research
- PMID: 30940237
- DOI: 10.1017/S0140525X18001231
Reductionist thinking and animal models in neuropsychiatric research
Abstract
Reductionist thinking in neuroscience is manifest in the widespread use of animal models of neuropsychiatric disorders. Broader investigations of diverse behaviors in non-model organisms and longer-term study of the mechanisms of plasticity will yield fundamental insights into the neurobiological, developmental, genetic, and environmental factors contributing to the "massively multifactorial system networks" which go awry in mental disorders.
Comment in
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Reductionism in retreat.Behav Brain Sci. 2019 Jan;42:e32. doi: 10.1017/S0140525X18002091. Behav Brain Sci. 2019. PMID: 30940245
Comment on
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Brain disorders? Not really: Why network structures block reductionism in psychopathology research.Behav Brain Sci. 2018 Jan 24;42:e2. doi: 10.1017/S0140525X17002266. Behav Brain Sci. 2018. PMID: 29361992
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