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Review
. 2019 May 13;58(20):6488-6490.
doi: 10.1002/anie.201902132. Epub 2019 Apr 3.

Radical Umpolung: Efficient Options for the Synthesis of 1,4-Dicarbonyl Compounds

Xiang-Yu Chen  1 , Dieter Enders  1
Affiliations
Review

Radical Umpolung: Efficient Options for the Synthesis of 1,4-Dicarbonyl Compounds

Xiang-Yu Chen et al. Angew Chem Int Ed Engl. .

Abstract

Radical developments: Photochemical/secondary amine dual catalysis has proven to be an efficient strategy for radical umpolung reactions. Two new processes provide an elegant solution to a long-standing chemoselectivity problem for the synthesis of 1,4-dicarbonyl compounds.

Keywords: Stetter reaction; dicarbonyl compounds; organocatalysis; photocatalysis; umpolung.

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