Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2019 Apr 2;29(4):785-786.
doi: 10.1016/j.cmet.2019.03.006.

Metabolic Adaptation Fuels Lymph Node Metastasis

Jessalyn M Ubellacker  1 , Sean J Morrison  2
Affiliations
Free article
Comment

Metabolic Adaptation Fuels Lymph Node Metastasis

Jessalyn M Ubellacker et al. Cell Metab. .
Free article

Abstract

Many cancers metastasize regionally through lymphatics before metastasizing systemically through blood vessels. However, metastasis through blood has been studied much more extensively than metastasis through lymph. Recently in Science, Lee et al. (2019) offered new insight into lymph node metastasis by showing that melanoma cells must undergo metabolic changes during this process and that it is driven by localized accumulation of bile acids.

PubMed Disclaimer

Comment on

Publication types

LinkOut - more resources