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. 2019 Apr 3;19(1):35.
doi: 10.1186/s12902-019-0360-9.

Adherence to antidiabetic medication and factors associated with non-adherence among patients with type-2 diabetes mellitus in two regional hospitals in Cameroon

Leopold Ndemnge Aminde  1   2 , Maxime Tindong  3 , Calypse A Ngwasiri  4   5 , Jeannine A Aminde  6   7 , Tsi Njim  8   9 , Azingala Ajua Fondong  7 , Noah Fongwen Takah  10
Affiliations

Adherence to antidiabetic medication and factors associated with non-adherence among patients with type-2 diabetes mellitus in two regional hospitals in Cameroon

Leopold Ndemnge Aminde et al. BMC Endocr Disord. .

Abstract

Background: Diabetes mellitus is a growing cause of disease burden globally. Its management is multifaceted, and adherence to pharmacotherapy is known to play a significant role in glycaemic control. Data on medication adherence among affected patients is unknown in Cameroon. In this study, the level of adherence and factors influencing non-adherence to antidiabetic medication among patients with type-2 diabetes was assessed.

Methods: A hospital-based cross-sectional study among adult patients receiving care in the diabetic clinics of the Limbe and Bamenda Regional Hospitals in Cameroon was conducted. Medication adherence was assessed using the Medication Compliance Questionnaire (MCQ). Factors associated with non-adherence to medication were determined using basic and adjusted multivariable logistic regression models.

Results: A total of 195 patients with type 2 diabetes were recruited. The prevalence of non-adherence to medication was 54.4% [95% confidence interval (CI): 47.1-61.5%]. In multivariable analysis, age > 60 years (aO.R. = 0.48, 95% CI: 0.25-0.94), alcohol consumption (aO.R. = 2.13, 95% CI: 1.10-4.14) and insulin alone therapy (aO.R. = 2.85, 95% CI: 1.01-8.08) were associated with non-adherence. Patients attributed their non-adherence to forgetfulness (55.6%), lack of finances (38.2%) and disappearance of symptoms (14.2%).

Conclusions: Adherence to anti-diabetic medication is poor in this study with more than half of participants being non-adherent. Urgent interventions are required to tackle this problem in combined efforts to stem this looming diabetes epidemic.

Keywords: Cameroon; Medication adherence; Type 2 diabetes.

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Conflict of interest statement

Ethics approval and consent to participate

Ethical approval for this study was provided by the Regional Delegation of the Ministry of Health. All patients provided written informed consent to participate in the study.

Consent for publication

Not applicable

Competing interests

The authors declare that they have no competing interests.

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References

    1. International Diabetes Federation. Diabetes Atlas: International Diabetes Federation 2015.
    1. Hu FB, Satija A, Manson JE. Curbing the diabetes pandemic: the need for global policy solutions. Jama. 2015;313(23):2319–2320. doi: 10.1001/jama.2015.5287. - DOI - PMC - PubMed
    1. Malik VS, Willett WC, Hu FB. Global obesity: trends, risk factors and policy implications. Nat Rev Endocrinol. 2013;9(1):13–27. doi: 10.1038/nrendo.2012.199. - DOI - PubMed
    1. Bigna JJ, Nansseu JR, Katte JC, Noubiap JJ. Prevalence of prediabetes and diabetes mellitus among adults residing in Cameroon: a systematic review and meta-analysis. Diabetes Res Clin Pract. 2018;137:109–118. doi: 10.1016/j.diabres.2017.12.005. - DOI - PubMed
    1. GBD 2016 DALYs and HALE Collaborators Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016. Lancet (London, England) 2017;390(10100):1260–1344. doi: 10.1016/S0140-6736(17)32130-X. - DOI - PMC - PubMed