Position statement: LEPROSY: Diagnosis, treatment and follow-up
- PMID: 30945360
- DOI: 10.1111/jdv.15569
Position statement: LEPROSY: Diagnosis, treatment and follow-up
Abstract
Background: Leprosy or Hansen's disease is a chronic infection caused by Mycobacterium leprae (M. leprae) or Mycobacterium lepromatosis (M. lepromatosis). In Europe, most of the leprosy cases are imported. However, occasionally a case is diagnosed in one of the old endemic foci. Leprosy is often not suspected because it is no longer emphasized in the medical curricula. Attention shifted from leprosy to tuberculosis and human immunodeficiency virus infections in the late 20th century, whereby the WHO leprosy programme was toned down in the conviction that leprosy was all but eliminated. The result of unawareness is a harmful doctor's delay.
Material and methods: This paper focusses on clinical diagnosis, complications and treatment based on literature and experience.
Results: It mentions the value of laboratory tests in classification, follow-up and detection of relapses. It discusses the etiopathology.
Conclusion: This is a position statement.
© 2019 European Academy of Dermatology and Venereology.
Comment in
-
Letter to editor in response to the article 'Position statement: LEPROSY: diagnosis, treatment and follow-up'.J Eur Acad Dermatol Venereol. 2020 Feb;34(2):e72-e73. doi: 10.1111/jdv.15948. Epub 2019 Oct 10. J Eur Acad Dermatol Venereol. 2020. PMID: 31505055 No abstract available.
Similar articles
-
Treatment of leprosy/Hansen's disease in the early 21st century.Dermatol Ther. 2009 Nov-Dec;22(6):518-37. doi: 10.1111/j.1529-8019.2009.01274.x. Dermatol Ther. 2009. PMID: 19889136 Review.
-
[Hansen's disease: case report and review of literature].Rev Chilena Infectol. 2008 Feb;25(1):64-9. Epub 2008 Feb 8. Rev Chilena Infectol. 2008. PMID: 18273528 Review. Spanish.
-
Reversible Cause of Neuropathy and Monoclonal Gammopathy of Renal Significance.Am J Med. 2020 May;133(5):576-579. doi: 10.1016/j.amjmed.2019.10.017. Epub 2019 Nov 9. Am J Med. 2020. PMID: 31712097 No abstract available.
-
[Leprosy – an old infectious disease with unsolved matters].Med Monatsschr Pharm. 2016 Dec;39(12):522-6. Med Monatsschr Pharm. 2016. PMID: 29979513 Review. German.
-
Lest we forget Hansen's disease (leprosy): an unusual presentation with an acute onset of inflammatory polyarthritis and the rheumatology experience.Int J Rheum Dis. 2009 Apr;12(1):64-9. doi: 10.1111/j.1756-185X.2009.01382.x. Int J Rheum Dis. 2009. PMID: 20374320
Cited by
-
Identification of sensitive indicators in immune response for leprosy affected patients: An observational clinical study of safety and immunogenicity of influenza vaccine.Medicine (Baltimore). 2021 Aug 6;100(31):e26744. doi: 10.1097/MD.0000000000026744. Medicine (Baltimore). 2021. PMID: 34397815 Free PMC article.
-
Case Report: Necrotizing Erythema Nodosum as a Manifestation of Lepromatous Leprosy Relapse 50 Years after the Initial Infection.Am J Trop Med Hyg. 2023 May 30;109(1):53-56. doi: 10.4269/ajtmh.22-0701. Print 2023 Jul 5. Am J Trop Med Hyg. 2023. PMID: 37253443 Free PMC article.
-
Next-generation sequencing-assisted diagnosis of a case of leprosy misdiagnosed as erythema multiforme.Ann Clin Microbiol Antimicrob. 2022 Sep 7;21(1):40. doi: 10.1186/s12941-022-00532-4. Ann Clin Microbiol Antimicrob. 2022. PMID: 36071525 Free PMC article.
-
Silent peripheral neuropathy determined by high-resolution ultrasound among contacts of patients with Hansen's disease.Front Med (Lausanne). 2023 Jan 17;9:1059448. doi: 10.3389/fmed.2022.1059448. eCollection 2022. Front Med (Lausanne). 2023. PMID: 36733931 Free PMC article.
-
Adverse reactions induced by MDT/WHO (Rifampicin+Clofazimine+Dapsone) and ROM (Rifampicin+Ofloxacin+Minocycline) regimens used in the treatment of leprosy: a cohort study in a National Reference Center in Brazil.Front Pharmacol. 2024 Mar 7;15:1346169. doi: 10.3389/fphar.2024.1346169. eCollection 2024. Front Pharmacol. 2024. PMID: 38515839 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical