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. 2019 Apr 3;102(1):6-8.
doi: 10.1016/j.neuron.2019.03.016.

Managing Neuronal Ensembles: Somatostatin Interneuron Subpopulations Shape and Protect Cortical Neuronal Ensembles for Learning

Melissa Serrano  1 , Pico Caroni  2
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Managing Neuronal Ensembles: Somatostatin Interneuron Subpopulations Shape and Protect Cortical Neuronal Ensembles for Learning

Melissa Serrano et al. Neuron. .
Free article

Abstract

Learning is accompanied by temporal compression and sharpening of neuronal firing sequences. In this issue of Neuron, Adler et al. (2019), using a motor skill paradigm and its variant, uncover a dual role for somatostatin interneuron regulation to support ensemble compaction and protection in learning.

Keywords: VIP interneuron; calcium imaging; dendritic plasticity; motor skill learning; neuronal ensembles; somatostatin interneuron; spine plasticity.

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