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Comment
. 2019 May;35(5):338-340.
doi: 10.1016/j.pt.2019.03.007. Epub 2019 Apr 1.

Interrupting Toxoplasma's Regularly Scheduled Program of Egress

Vern B Carruthers  1
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Comment

Interrupting Toxoplasma's Regularly Scheduled Program of Egress

Vern B Carruthers. Trends Parasitol. 2019 May.

Abstract

Although many cellular components of the Ca2+ signaling pathway dictating Toxoplasma gondii egress have been identified, whether the parasite secretes protein activators of this pathway remained unknown. Bisio et al. (Nat. Microbiol. 2019;4:420-428) identify a parasite-secreted diacylglycerol kinase as a key upstream activator of signaling for 'programmed' egress from host cells.

Keywords: Ca(2+) signaling; parasite egress.

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