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doi: 10.1016/j.molcel.2019.03.017.
Structure and Function in Drosophila Chromosomes: Visualizing Topological Domains
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- PMID: 30951650
- DOI: 10.1016/j.molcel.2019.03.017
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Structure and Function in Drosophila Chromosomes: Visualizing Topological Domains
Mol Cell.
.
Free article
Abstract
Cardozo Gizzi et al. (2019) develop a new sequential imaging methodology (Hi-M) for observing chromosome structure in the Drosophila blastoderm and find that topological domains in single nuclei change in response to transcriptional activation.
Published by Elsevier Inc.
Comment on
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Microscopy-Based Chromosome Conformation Capture Enables Simultaneous Visualization of Genome Organization and Transcription in Intact Organisms.Mol Cell. 2019 Apr 4;74(1):212-222.e5. doi: 10.1016/j.molcel.2019.01.011. Epub 2019 Feb 19. Mol Cell. 2019. PMID: 30795893
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