TREMendous Macrophages Inhibit Hair Growth
- PMID: 30951655
- DOI: 10.1016/j.stem.2019.03.014
TREMendous Macrophages Inhibit Hair Growth
Abstract
Tissue-resident immune cells with potent sensing and effector functions are well-placed to fundamentally aid tissue homeostasis via crosstalk with stem cells. In this issue of Cell Stem Cell, Wang et al. (2019) identify a dermis-resident TREM2+ macrophage subpopulation that promotes hair follicle stem cell quiescence via cytokine-mediated JAK-STAT signaling.
Copyright © 2019 Elsevier Inc. All rights reserved.
Comment on
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A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth.Cell Stem Cell. 2019 Apr 4;24(4):654-669.e6. doi: 10.1016/j.stem.2019.01.011. Epub 2019 Mar 28. Cell Stem Cell. 2019. PMID: 30930146
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