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Comment
. 2019 Apr 4;24(4):501-502.
doi: 10.1016/j.stem.2019.03.014.

TREMendous Macrophages Inhibit Hair Growth

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TREMendous Macrophages Inhibit Hair Growth

Tim Dalessandri et al. Cell Stem Cell. .
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Abstract

Tissue-resident immune cells with potent sensing and effector functions are well-placed to fundamentally aid tissue homeostasis via crosstalk with stem cells. In this issue of Cell Stem Cell, Wang et al. (2019) identify a dermis-resident TREM2+ macrophage subpopulation that promotes hair follicle stem cell quiescence via cytokine-mediated JAK-STAT signaling.

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