Counting Calories: The Cost of Inflammation
- PMID: 30951664
- DOI: 10.1016/j.cell.2019.03.022
Counting Calories: The Cost of Inflammation
Abstract
A relationship between thermoregulation, metabolism, and the host response to infections has long been appreciated. In this study, Ganeshan and colleagues discover that the immune system regulates body temperature as a strategy to regulate metabolic rate, which in turn promotes tolerance to inflammatory damage.
Copyright © 2019. Published by Elsevier Inc.
Comment on
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Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance.Cell. 2019 Apr 4;177(2):399-413.e12. doi: 10.1016/j.cell.2019.01.050. Epub 2019 Mar 7. Cell. 2019. PMID: 30853215 Free PMC article.
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