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Comment
. 2019 Apr 4;177(2):225-227.
doi: 10.1016/j.cell.2019.03.020.

Explicating Exosomes: Reclassifying the Rising Stars of Intercellular Communication

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Comment

Explicating Exosomes: Reclassifying the Rising Stars of Intercellular Communication

Stefano Pluchino et al. Cell. .
Free article

Abstract

There is growing interest surrounding the diagnostic and therapeutic potential of exosomes, but a definitive description of these extracellular vesicles remains elusive. In this issue, Jeppesen et al. characterize exosomes following a strict isolation protocol and in so doing challenge several of the accepted properties of these agents of intercellular communication.

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  • Reassessment of Exosome Composition.
    Jeppesen DK, Fenix AM, Franklin JL, Higginbotham JN, Zhang Q, Zimmerman LJ, Liebler DC, Ping J, Liu Q, Evans R, Fissell WH, Patton JG, Rome LH, Burnette DT, Coffey RJ. Jeppesen DK, et al. Cell. 2019 Apr 4;177(2):428-445.e18. doi: 10.1016/j.cell.2019.02.029. Cell. 2019. PMID: 30951670 Free PMC article.

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