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Review
. 2019 May;39(2):205-219.
doi: 10.1016/j.iac.2018.12.002.

Recent Diagnosis Techniques in Pediatric Asthma: Impulse Oscillometry in Preschool Asthma and Use of Exhaled Nitric Oxide

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Review

Recent Diagnosis Techniques in Pediatric Asthma: Impulse Oscillometry in Preschool Asthma and Use of Exhaled Nitric Oxide

Karen M McDowell. Immunol Allergy Clin North Am. 2019 May.

Abstract

Objective measures of lung function are important in the diagnosis and management of asthma. Spirometry, the pulmonary function test most widely used in asthma, requires respiratory maneuvers that may be difficult for preschoolers. Impulse oscillometry (IOS) is a noninvasive method of measuring lung function during tidal breathing; hence, IOS is an ideal test for use in preschool asthma. Fractional exhaled nitric oxide (FeNO) levels correspond to eosinophilic inflammation and predict responsiveness to corticosteroids. Basic concepts of IOS, methodology, and interpretation, including available normative values, and recent findings regarding FeNO are reviewed in this article.

Keywords: Coherence; Impedance; Impulse oscillometry; Preschool asthma; Pulmonary function testing; Reactance; Resistance; Tidal breathing.

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