The effect of emergency department crowding on lung-protective ventilation utilization for critically ill patients

Abstract

Objective: To measure effects of ED crowding on lung-protective ventilation (LPV) utilization in critically ill ED patients.

Methods: This is a retrospective cohort study of adult mechanically ventilated ED patients admitted to the medical intensive care unit (MICU), over a 3.5-year period at a single academic tertiary care hospital. Clinical data, including reason for intubation, severity of illness (MPM₀-III), acute respiratory distress syndrome (ARDS) risk score (EDLIPS), and ventilator settings were extracted via electronic query of electronic health record and standardized chart abstraction. Crowding metrics were obtained at 5-min intervals and averaged over the ED stay, stratified by acuity and disposition. Multivariate logistic regression was used to predict likelihood of LPV prior to ED departure.

Results: Mechanical ventilation was used in 446 patients for a median ED duration of 3.7 h (interquartile ratio, IQR, 2.3, 5.6). Mean MPM₀-III score was 32.5 ± 22.7, with high risk for ARDS (EDLIPS ≥5) seen in 373 (82%) patients. Initial and final ED ventilator settings differed in 134 (30.0%) patients, of which only 47 (35.1%) involved tidal volume changes. Higher percentages of active ED patients (workup in-progress) and those requiring eventual admission were associated with lower odds of LPV utilization by ED departure (OR 0.97, 95%CI 0.94-1.00; OR 0.97, 95%CI 0.94-1.00, respectively). In periods of high volume, ventilator adjustments to settings other than the tidal volume were associated with higher odds of LPV utilization. Reason for intubation, MPM₀-III, and EDLIPS were not associated with LPV utilization, with no interactions detected in times of crowding.

Conclusions: ED patients remain on suboptimal tidal volume settings with infrequent ventilator adjustments during the ED stay. Hospitals should focus on both systemic factors and bedside physician and/or respiratory therapist interventions to increase LPV utilization in times of ED boarding and crowding for all patients.

FIGURE 1.. Tidal volume from Initial ED settings, ED departure, and ICU Arrival

The range of tidal volume settings, in cc/kg predicted body weight, in the ED and on ICU arrival are shown in this figure. Patients remain on similar settings throughout their ED stay and after ICU admission, with only 57% placed on LPV strategy.

FIGURE 2.. Probability of LPV settings at ED departure, with increasing ED patient volume, stratified by presence or absence of documented ventilator adjustments

Though increased ED patient volume is associated with decreasing odds of LPV settings, documented ventilator adjustments, other than TV setting, mitigates this decline.