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Case Reports
. 2019 Jan 14;32(1):90-92.
doi: 10.1080/08998280.2018.1528962. eCollection 2019 Jan.

Milia within resolving bullous pemphigoid lesions

Sima Amin  1 , Connie T Fiore  2 , So Yeon Paek  1   2
Affiliations
Case Reports

Milia within resolving bullous pemphigoid lesions

Sima Amin et al. Proc (Bayl Univ Med Cent). .

Abstract

Bullous pemphigoid (BP) is a blistering dermatosis characterized by an autoimmune response to two hemidesmosomal proteins, BP180 and BP230. We describe a case of an 80-year-old man diagnosed with BP by clinical features, histopathology, and immunosorbent assay who developed milia within resolving BP lesions. Milia formation during recovery is common in cases of mucous membrane pemphigoid and epidermolysis bullosa acquisita but has rarely been reported in cases of BP.

Keywords: Bullous pemphigoid; milium formation; postbullous milia.

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Figures

Figure 1.
Figure 1.
(a) Punch biopsy of the lesion revealing a subepidermal bulla with underlying chronic inflammation and numerous eosinophils, consistent with bullous pemphigoid (hematoxylin-eosin, original magnification ×100). Direct immunofluorescence biopsy showed linear deposits of (b) C3 (×400) and (c) immunoglobulin G (×400) at the dermal-epidermal junction.
Figure 2.
Figure 2.
(a) Pinpoint white papules in grouped and annular distribution along the periphery of resolving bullous pemphigoid lesions noted on the thighs (shown), trunk, and arms. (b) Histology of a 4-mm punch biopsy specimen of a lesion on the left upper arm showing a dermal unilocular cyst lined by stratified squamous epithelium with a granular cell layer and basket-woven keratin debris (hematoxylin-eosin, original magnification ×40).
See this image and copyright information in PMC

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