Neoplastic Pathogenesis Associated with Cigarette Carcinogens
- PMID: 30956908
- PMCID: PMC6436676
- DOI: 10.7759/cureus.3955
Neoplastic Pathogenesis Associated with Cigarette Carcinogens
Abstract
Cigarette smoke is widely regarded as a carcinogenic agent; thus, the incidence of relative neoplasms correlates to cigarette smoking (CS) on a global level. While CS is most commonly associated with carcinomas of the upper and lower respiratory tracts, studies have also associated CS with the pathogenesis of a variety of non-respiratory related neoplasms. The tobacco smoke emitted from cigarettes contains carcinogenic substances that can be harmful to the normal physiology of the human body. This study will elaborate on the incidence and etiology of carcinomas, as well as discuss, in detail, the role of tobacco in the pathogenesis of oral, esophageal, lung, gastric, pancreatic, renal, and bladder carcinomas.
Keywords: carcinogenic agent; cigarette; neoplasms; tobacco.
Conflict of interest statement
The authors have declared that no competing interests exist.
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References
-
- Tobacco. [Nov;2018 ];https://www.who.int/news-room/fact-sheets/detail/tobacco WHO. 2018
-
- Smoking and tobacco use. https://www.cdc.gov/tobacco/data_statistics/fact_sheets/fast_facts/index... Centers for Disease Control and Prevention. 2018;January 23, 2019
-
- Harms of cigarette smoking and health benefits of quitting. [Nov;2018 ];https://www.cancer.gov/about-cancer/causes-prevention/risk/tobacco/cessa... National Cancer Institute. 2017
-
- CDC: 40% of cancer cases in US might be linked to tobacco. [Nov;2018 ];Simon S. https://www.cancer.org/latest-news/cdc-40-percent-of-cancer-cases-in-us-... American Cancer Society. 2016
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