Immunometabolism Sentinels: Gut Surface T-Cells Regulate GLP-1 Availability
- PMID: 30958533
- PMCID: PMC6480433
- DOI: 10.1210/en.2019-00215
Immunometabolism Sentinels: Gut Surface T-Cells Regulate GLP-1 Availability
Comment on
-
Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease.Nature. 2019 Feb;566(7742):115-119. doi: 10.1038/s41586-018-0849-9. Epub 2019 Jan 30. Nature. 2019. PMID: 30700910 Free PMC article.
References
-
- Lutter L, Hoytema van Konijnenburg DP, Brand EC, Oldenburg B, van Wijk F. The elusive case of human intraepithelial T cells in gut homeostasis and inflammation. Nat Rev Gastroenterol Hepatol. 2018;15(10):637–649. - PubMed
-
- He S, Kahles F, Rattik S, Nairz M, McAlpine CS, Anzai A, Selgrade D, Fenn AM, Chan CT, Mindur JE, Valet C, Poller WC, Halle L, Rotllan N, Iwamoto Y, Wojtkiewicz GR, Weissleder R, Libby P, Fernández-Hernando C, Drucker DJ, Nahrendorf M, Swirski FK. Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease. Nature. 2019;566(7742):115–119. - PMC - PubMed
-
- MacDonald PE, El-Kholy W, Riedel MJ, Salapatek AM, Light PE, Wheeler MB. The multiple actions of GLP-1 on the process of glucose-stimulated insulin secretion. Diabetes. 2002;51(Suppl 3):S434–S442. - PubMed
-
- Yusta B, Baggio LL, Koehler J, Holland D, Cao X, Pinnell LJ, Johnson-Henry KC, Yeung W, Surette MG, Bang KW, Sherman PM, Drucker DJ. GLP-1R agonists modulate enteric immune responses through the intestinal intraepithelial lymphocyte GLP-1R. Diabetes. 2015;64(7):2537–2549. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
