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. 2019 Jan 31;20(2):153-156.
doi: 10.5152/TurkThoracJ.2018.18059. Print 2019 Apr.

Spontaneous Partial Regression of a Carcinoid Tumor: Radiology May Not Capture the Real Picture

Ashok Kuwal  1 , Nishant Chauhan  2 , Naveen Dutt  2 , Poonam Elhence  3 , Manish Advani  1 , Sunil Kumar  4
Affiliations

Spontaneous Partial Regression of a Carcinoid Tumor: Radiology May Not Capture the Real Picture

Ashok Kuwal et al. Turk Thorac J. .

Abstract

A partial or complete resolution of the neoplastic lesion, either spontaneously or in the presence of therapy that is considered inadequate to exert significant influence on the growth of the neoplastic lesion, is considered a spontaneous regression. This phenomenon is extremely rare in lung neoplasms. A close follow up with imaging along with bronchoscopy and a biopsy of the lesion is essential, as they may have potential for distant spread even during radiological regression. Here, we report a case of a partial resolution of a bronchial carcinoid tumor that had a high mitotic activity and was resected.

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Conflict of interest statement

Conflict of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
CECT thorax showed 1.7×2.1×2.2 cm well defined, mildly enhancing lesion in the right lower lobe immediatelyafter the division of the superior segment with coarse calcifications CECT: contrast enhanced computed tomography
Figure 2
Figure 2
CECT thorax (2015) showed a decrease in the size of the lesion (1.5×1.9×1.8 cm) CECT: contrast enhanced computed tomography
Figure 3
Figure 3
Diagnostic bronchoscopy showed a large, rounded, exophytic mass lesion completely filling the lumen of the right lower lobe bronchus after the take off of the superior segment bronchus
Figure 4
Figure 4
Narrow band imaging bronchoscopy revealed prominent dilated and tortuous vessels over the mass lesion
Figure 5
Figure 5
Histopathological examination of the endobronchial biopsy specimen exhibited rounded cells with abundant eosinophilic cytoplasm and central nuclei, which displayed a characteristic salt andpepper chromatin. There wasno necrosis, hemorrhage, or mitotic activity
Figure 6
Figure 6
IHC-chromogranin positivity IHC: immunohistochemistry
Figure 7
Figure 7
IHC-cytokeratin positivity IHC: immunohistochemistry
See this image and copyright information in PMC

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