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Review
. 2018 Apr 30;9(2):90-97.
doi: 10.1016/j.jtcme.2018.03.003. eCollection 2019 Apr.

The medical perspective of cupping therapy: Effects and mechanisms of action

Abdullah M N Al-Bedah  1 , Ibrahim S Elsubai  1 , Naseem Akhtar Qureshi  1 , Tamer Shaban Aboushanab  1 , Gazzaffi I M Ali  1 , Ahmed Tawfik El-Olemy  1   2 , Asim A H Khalil  1 , Mohamed K M Khalil  1 , Meshari Saleh Alqaed  1
Affiliations
Review

The medical perspective of cupping therapy: Effects and mechanisms of action

Abdullah M N Al-Bedah et al. J Tradit Complement Med. .

Abstract

Cupping Therapy (CT) is an ancient method and currently used in the treatment of a broad range of medical conditions. Nonetheless the mechanism of action of (CT) is not fully understood. This review aimed to identify possible mechanisms of action of (CT) from modern medicine perspective and offer possible explanations of its effects. English literature in PubMed, Cochrane Library and Google Scholar was searched using key words. Only 223 articles identified, 149 records screened, and 74 articles excluded for irrelevancy. Only 75 full-text articles were assessed for eligibility, included studies in this review were 64. Six theories have been suggested to explain the effects produced by cupping therapy. Pain reduction and changes in biomechanical properties of the skin could be explained by "Pain-Gate Theory", "Diffuse Noxious Inhibitory Controls" and "Reflex zone theory". Muscle relaxation, changes in local tissue structures and increase in blood circulation might be explained by "Nitric Oxide theory". Immunological effects and hormonal adjustments might be attributed to "Activation of immune system theory". Releasing of toxins and removal of wastes and heavy metals might be explained by "Blood Detoxification Theory". These theories may overlap or work interchangeably to produce various therapeutic effects in specific ailments and diseases. Apparently, no single theory exists to explain the whole effects of cupping. Further researches are needed to support or refute the aforesaid theories, and also develop innovative conceptualizations of (CT) in future.

Keywords: Cupping; Effects; Hijama; Mechanisms of action.

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Figures

Image 1
Graphical abstract
Fig. 1
Fig. 1
Prisma flow diagram.
Fig. 2
Fig. 2
Links between cupping therapy effects and mechanisms of action theories.
See this image and copyright information in PMC

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References

    1. Ullah K., Younis A., Wali M. An investigation into the effect of cupping therapy as a treatment for anterior knee pain and its potential role in health promotion. Internet J Alternative Med. 2006;4:1.
    1. Al-Bedah A.M., Aboushanab T.S., Alqaed M.S. Classification of Cupping Therapy: a tool for modernization and standardization. J. Compl. Alternative Med. Res. 2016;1 1:1-0.
    1. Kim Jong-In, Lee Myeong Soo, Lee Dong-Hyo, Boddy Kate, Ernst Edzard. Evidence-based Complementary and Alternative Medicine. 2011. Cupping for treating pain: a systematic review. - PMC - PubMed
    1. Ghods R., Sayfouri N., Ayati M.H. Anatomical features of the interscapular area where wet cupping therapy is done and its possible relation to acupuncture meridians. J Acupunct Meridian Stud. 2016;9:290–296. 6. - PubMed
    1. Rozenfeld Evgeni, Kalichman Leonid. New is the well-forgotten old: the use of dry cupping in musculoskeletal medicine. J Bodyw Mov Ther. 2016;20(1):173–178. - PubMed