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Case Reports
. 2020 Jan;104(1):172-175.
doi: 10.1097/TP.0000000000002745.

Renal Lymphangiectasia in the Transplanted Kidney: Case Series and Literature Review

Mark T Dawidek  1 , Shahid Aquil  1   2   3 , Rafid Alogaili  1   2   3 , Manal Gabril  1   4 , Madeleine Moussa  1   4 , Alp Sener  1   2   3 , Patrick P Luke  1   2   3
Affiliations
Case Reports

Renal Lymphangiectasia in the Transplanted Kidney: Case Series and Literature Review

Mark T Dawidek et al. Transplantation. 2020 Jan.

Abstract

Background: Renal lymphangiectasia is a rare and poorly understood lymphatic disease associated with lymphatic dilation and leakage. To our knowledge, no cases have been described in the context of a transplanted kidney.

Methods: We describe 2 cases of renal lymphangiectasia in transplanted kidneys, both from pediatric donors.

Results: The cases of allograft lymphangiectasia are characterized by severe, symptomatic ascites refractory to attempts at medical and surgical management, and ultimately requiring allograft nephrectomy.

Conclusions: While lymphatic complications, particularly lymphoceles, are not uncommon in renal transplantation, lymphangiectasia is a distinct condition which should be considered in renal transplant patients with ascites, after all other sources have been ruled out.

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References

    1. Bazari H, Attar EC, Dahl DM, et al. Case records of the massachusetts general hospital. Case 23-2010. A 49-year-old man with erythrocytosis, perinephric fluid collections, and renal failure. N Engl J Med. 2010; 363:463–475
    1. Pandya VK, Shah MK, Gandhi SP, et al. Bilateral renal lymphangiectasia. J Clin Diagn Res. 2016; 10:TD01–TD02
    1. Pollack SF, Geffrey AL, Thiele EA, et al. Primary intestinal lymphangiectasia treated with rapamycin in a child with tuberous sclerosis complex (TSC). Am J Med Genet A. 2015; 167A:2209–2212
    1. Ishikawa Y, Akasaka Y, Kiguchi H, et al. The human renal lymphatics under normal and pathological conditions. Histopathology. 2006; 49:265–273
    1. Wong BW, Zecchin A, García-Caballero M, et al. Emerging concepts in organ-specific lymphatic vessels and metabolic regulation of lymphatic development. Dev Cell. 2018; 45:289–301

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