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. 2018 Apr 14;10(4):438.
doi: 10.3390/polym10040438.

Study on the Use of Microbial Cellulose as a Biocarrier for 1,3-Dihydroxy-2-Propanone and Its Potential Application in Industry

Lidia Stasiak-Różańska  1 , Justyna Płoska  2
Affiliations

Study on the Use of Microbial Cellulose as a Biocarrier for 1,3-Dihydroxy-2-Propanone and Its Potential Application in Industry

Lidia Stasiak-Różańska et al. Polymers (Basel). .

Abstract

Can microbial cellulose (MC) be used as a bio-carrier for 1,3-dihydroxy-2-propanone (DHA)? The aim of this study was to examine the possibility of using MC as a biomaterial for DHA transferring into the stratum corneum and inducing changes in skin color. The MC patches were obtained from Gluconacetobacter xylinus strain and incubated in solutions with various concentrations of DHA (g·L-1: 20; 50; 80; 110) at 22 °C for 24 h. Afterwards; the patches were applied onto the skin for 15, 30, or 60 min. Skin color changes were assessed visually compared to a control patches without DHA. The intensity of skin color was increasing with the increase of DHA concentration and time of patches application. Application of MC patches with DHA (50 g·L-1) for 30 min ensured the color which was considered the closest to the desired natural tan effect. MC patches containing DHA can be biocarriers enabling DHA transport into the stratum corneum and causing skin color changes. Study results indicate a new possibility for industrial applications of MC; e.g., as a biocarrier in masking the symptoms of vitiligo or production of self-tanning agents in the form of masks.

Keywords: bacterial cellulose; biocarrier; biomaterial; dihydroxyacetone; microbial cellulose; vitiligo.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Microbial cellulose obtained from Gluconacetobacter xylinus strain, before removing bacterial cells (a), after removing bacterial cells (b).
Figure 2
Figure 2
Hands of the patient with vitiligo.
Figure 3
Figure 3
Process of preparing MC patches with DHA.
Figure 4
Figure 4
Results of the assessment of skin pigmentation changes conducted by 15 observers. Pigmentation intensity was rated from 0 to 5, where 0 means no color changes, and 5 means the darkest color compared to the control.
Figure 5
Figure 5
Skin coloring 12 h after removal of MC patches with DHA, which were applied for 30 min (concentration of DHA was expressed in %).
Figure 6
Figure 6
Skin area before (a), during (b) and after the application of MC with DHA (c) presents visible peripheral accentuation. Scale 1:2, 1 cm = 0.5 cm.
See this image and copyright information in PMC

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