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. 2018 Jun 19;10(6):682.
doi: 10.3390/polym10060682.

Sol-Gel Synthesis, Spectroscopic and Thermal Behavior Study of SiO₂/PEG Composites Containing Different Amount of Chlorogenic Acid

Michelina Catauro  1 , Elisabetta Tranquillo  2   3 , Roberta Risoluti  4 , Stefano Vecchio Ciprioti  5
Affiliations

Sol-Gel Synthesis, Spectroscopic and Thermal Behavior Study of SiO₂/PEG Composites Containing Different Amount of Chlorogenic Acid

Michelina Catauro et al. Polymers (Basel). .

Abstract

In this work, new phenol-based materials have been synthesized by the sol-gel method, in which different amounts of the phenolic antioxidant chlorogenic acid (CGA) (from 5 wt % to 20 wt %) were embedded in two different silica matrices: pure silica and silica-based hybrids materials, containing 50 wt % of polyethylene glycol (PEG). The incorporation of CGA in different sol-gel matrices might protect them from degradation, which could cause the loss of their properties. The two series of materials were chemically characterized by Fourier transform infrared (FTIR) spectroscopy. In addition, the thermal behavior of both series of materials containing CGA was studied by thermogravimetry under both air and inert N₂ flowing gas atmosphere. The bioactivity was evaluated by soaking the synthesized hybrids in a simulated body fluid, showing that the bioactivity of the silica matrix is not modified by the presence of PEG and CGA.

Keywords: FTIR; TG; bioactivity; chlorogenic acid; hybrids; sol-gel.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Flow chart of the sol-gel hybrid synthesis and the molar ratios between the reagents achieved in the sol.
Figure 2
Figure 2
Representative Fourier transform infrared (FTIR) spectra of: (a) pure polyethylene glycol (PEG); (b) SiO2/PEG50 wt %/chlorogenic acid (CGA)5 wt %; (c) SiO2/PEG50 wt %/CGA10 wt %; (d) SiO2/PEG50 wt %/CGA15 wt %; (e) SiO2/PEG50 wt %/CGA20 wt %; (f) pure SiO2.
Figure 3
Figure 3
Representative FTIR spectra of: (a) pure CGA; (b) SiO2/CGA5 wt %; (c) SiO2/PEG50 wt %/CGA5 wt %; (d) SiO2/PEG50 wt %/CGA10 wt %; (e) SiO2/PEG50 wt %/CGA15 wt %; (f) SiO2/PEG50 wt %/CGA20 wt %; (g) SiO2/CGA20 wt %.
Figure 4
Figure 4
Thermogravimetric (TG) curves of pure SiO2 and SiO2/CGA hybrids at 10 °C min−1 under a flowing atmosphere of: nitrogen (a); air (b).
Figure 5
Figure 5
TG curves of SiO2/PEG and SiO2/PEG/CGA hybrids at 10 °C min−1 under a flowing atmosphere of: nitrogen (a); air (b).
Figure 6
Figure 6
Representative FTIR spectra of (a) SiO2/PEG50 wt %/CGA5 wt %; (b) SiO2/PEG50 wt %/CGA10 wt %; (c) SiO2/PEG50 wt %/CGA15 wt %; (d) SiO2/PEG50 wt %/CGA20 wt % after 21 days of exposure to SBF.
See this image and copyright information in PMC

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