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Case Reports
. 2019 Feb;23(Suppl 1):122-125.
doi: 10.4103/jomfp.JOMFP_77_18.

Rhinocerebral mucormycosis associated with actinomycosis in a diabetic patient: A rare presentation

Sanda Usha Rani  1 , Yeluri Sivaranjani  1 , Manchikatla Praveen Kumar  2 , Guttikonda Venkateswara Rao  1
Affiliations
Case Reports

Rhinocerebral mucormycosis associated with actinomycosis in a diabetic patient: A rare presentation

Sanda Usha Rani et al. J Oral Maxillofac Pathol. 2019 Feb.

Abstract

Mucormycosis is an opportunistic fulminant fungal infection which mainly affects the immunocompromised individuals. It begins in the nose and paranasal sinuses due to the inhalation of fungal spores. The common predisposing factors include diabetes mellitus and immunosuppression. Actinomycosis is a bacterial infection caused by nonspore-forming, anaerobic or microaerophilic bacterial species of the genus Actinomyces. It is a suppurative and chronic granulomatous disease characterized by abscess formation, tissue fibrosis and draining sinuses rarely diagnosed in humans. A case of rhinocerebral mucormycosis associated with actinomycosis of the maxilla involving the palate in an uncontrolled diabetic patient is reported.

Keywords: Actinomycosis; diabetes mellitus; maxilla; mucormycosis.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Extraoral picture revealing diffused swelling with ill-defined borders
Figure 2
Figure 2
Intraorally necrotic bone was seen in the region of the palate with bony erosion of the maxillary arch
Figure 3
Figure 3
Computerized tomography scan revealed erosion of the anterior maxilla and midpalatal regions
Figure 4
Figure 4
Paranasal sinus view revealed moth-eaten appearance involving the upper anterior alveolar ridge
Figure 5
Figure 5
(a) Histopathology revealing numerous thick-walled, irregularly branching nonseptate hyphae in the background of necrotic tissue. (b) Club-shaped filaments forming a radiating rosette pattern
Figure 6
Figure 6
Surgical excision of necrotic bone and adjacent soft tissue
See this image and copyright information in PMC

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