Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 Apr 6;2019(4):rjz109.
doi: 10.1093/jscr/rjz109. eCollection 2019 Apr.

Metastatic acinic cell carcinoma of the parotid gland to the abdominal wall

Alexandros Poutoglidis  1 , Ioannis Pateras  2 , Vasiliki Kokkinou  3 , Petros Tziolas  4
Affiliations
Case Reports

Metastatic acinic cell carcinoma of the parotid gland to the abdominal wall

Alexandros Poutoglidis et al. J Surg Case Rep. .

Abstract

Acinic cell carcinoma (ACC) is a low-grade malignant salivary neoplasm. The parotid gland is the predominant site of origin. ACC has a tendency to recur and metastasize, rarely enough to soft tissue as well as other sites. Medical records of a 56-year-old male with a known history of acinic cell carcinoma of the left parotid gland were reviewed. This report aims to highlight the need for early clinical suspicion of the metastatic tendency of parotid gland ACC in patients' soft tissues, and the vigorous oncologic approach to any suspected metastatic deposits, as this is the standard of practice and only treatment.

PubMed Disclaimer

Figures

Figure 1:
Figure 1:
A 1.8 cm × 2 cm lesion (red arrow) revealed in CT scan within the subcutaneous fat.
Figure 2:
Figure 2:
The lesion (green arrow) appears cystic due to its central tumor necrosis (black arrow). Hematoxylin and eosin ×200.
Figure 3:
Figure 3:
The tumor cells are positive for chymotrypsin in immunohistochemistry. Immunostaining ×200.
See this image and copyright information in PMC

References

    1. Al-Zaher N, Obeid A, Al-Salam S, Al-Kayyali BS. Acinic cell carcinoma of the salivary glands: a literature review. Hematol Oncol Stem Cell Ther 2009;2:259–4. - PubMed
    1. Scherl C, Kato MG, Erkul E, Graboyes EM, Nguyen SA, Chi AC, et al. . Outcomes and prognostic factors for parotid acinic cell carcinoma: a National Cancer Database study of 2362 cases. Oral Oncol 2018;82:53–60. - PubMed
    1. Vidyadhara S, Shetty AP, Rajasekaran S. Widespread metastases from acinic cell carcinoma of parotid gland. Singapore Med J 2007;48:13–5. - PubMed
    1. Varsegi MF, Ravis SM, Hattab EM, Henley JD, Billings SD. Widespread cutaneous metastases from acinic cell carcinoma 20 years after primary presentation. J Cutan Pathol 2008;35:591–3. - PubMed
    1. Spencer ML, Neto AG, Fuller GN, Lunal MA. Intracranial extension of acinic cell carcinoma of the parotid gland. Arch Pathol Lab Med 2005;129:780. - PubMed

Publication types