Esthesioneuroblastoma
- PMID: 30969516
- Bookshelf ID: NBK539694
Esthesioneuroblastoma
Excerpt
Esthesioneuroblastoma, or olfactory neuroblastoma, is a rare malignant neoplasm of the sinonasal tract originating from the olfactory neuroepithelium with neuroblastic differentiation. It most often presents in the superior nasal cavity. Since its initial description in 1924 by Berger and Luc, there have been reports of more than 1000 cases of esthesioneuroblastoma worldwide. Esthesioneuroblastoma is a locally aggressive neoplasm and metastasizes by both hematogenous and lymphatic routes.
Copyright © 2025, StatPearls Publishing LLC.
Conflict of interest statement
Sections
- Continuing Education Activity
- Introduction
- Etiology
- Epidemiology
- Pathophysiology
- Histopathology
- History and Physical
- Evaluation
- Treatment / Management
- Differential Diagnosis
- Staging
- Prognosis
- Complications
- Consultations
- Deterrence and Patient Education
- Enhancing Healthcare Team Outcomes
- Review Questions
- References
References
-
- Arnold PM, Habib A, Newell K, Anderson KK. Esthesioneuroblastoma metastatic to the thoracic intradural and extradural space. Spine J. 2009 May;9(5):e1-5. - PubMed
-
- Svane-Knudsen V, Jørgensen KE, Hansen O, Lindgren A, Marker P. Cancer of the nasal cavity and paranasal sinuses: a series of 115 patients. Rhinology. 1998 Mar;36(1):12-4. - PubMed
-
- Holland H, Koschny R, Krupp W, Meixensberger J, Bauer M, Kirsten H, Ahnert P. Comprehensive cytogenetic characterization of an esthesioneuroblastoma. Cancer Genet Cytogenet. 2007 Mar;173(2):89-96. - PubMed
-
- Riazimand SH, Brieger J, Jacob R, Welkoborsky HJ, Mann WJ. Analysis of cytogenetic aberrations in esthesioneuroblastomas by comparative genomic hybridization. Cancer Genet Cytogenet. 2002 Jul 01;136(1):53-7. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Medical