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Book

Cholinergic Toxicity(Archived)

Erica L. Hudson, Elizabeth B. Jones  1
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Cholinergic Toxicity(Archived)

Erica L. Hudson et al.
Free Books & Documents

Excerpt

Cholinergic toxicity is caused by medications, drugs, and substances that stimulate, enhance, or mimic the neurotransmitter acetylcholine. Acetylcholine is the primary neurotransmitter of the parasympathetic nervous system. Acetylcholine stimulates muscarinic and nicotinic receptors to cause muscle contraction and glandular secretions. Cholinergic toxicity occurs when too much acetylcholine is present in the receptor synapse, leading to excessive parasympathetic effects.

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Conflict of interest statement

Disclosure: Erica Hudson declares no relevant financial relationships with ineligible companies.

Disclosure: Elizabeth Jones declares no relevant financial relationships with ineligible companies.

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