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Granuloma faciale is a rare, benign inflammatory skin disease that usually presents as isolated, well-defined reddish-brown to violaceous asymptomatic papules, nodules, or plaques with follicular accentuation and telangiectasia. This skin disorder was first described as “eosinophilic granuloma” in 1945 by Wigley JE. Granuloma faciale typically affects middle-aged white men but has been reported in individuals ranging from the 2nd to the 7th decade of life. Childhood cases have also been documented. The condition typically presents as a single lesion on the face, but multiple lesions or extrafacial involvement may also occur. Extrafacial localizations include the scalp, trunk, nasal cavity, or extremities. Facial lesions most frequently appear on the forehead, nose, or cheeks.
Wigley JE. Eosinophilic Granuloma. ? Sarcoid of Boeck. Proc R Soc Med. 1945 Jan;38(3):125-6.
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Oliveira CC, Ianhez PE, Marques SA, Marques ME. Granuloma faciale: clinical, morphological and immunohistochemical aspects in a series of 10 patients. An Bras Dermatol. 2016 Nov-Dec;91(6):803-807.
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Ortonne N, Wechsler J, Bagot M, Grosshans E, Cribier B. Granuloma faciale: a clinicopathologic study of 66 patients. J Am Acad Dermatol. 2005 Dec;53(6):1002-9.
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Deen J, Moloney TP, Muir J. Extrafacial Granuloma Faciale: A Case Report and Brief Review. Case Rep Dermatol. 2017 May-Aug;9(2):79-85.
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Ma S, Liu H, Zhang F. Diffuse granuloma faciale. Int J Dermatol. 2023 Jul;62(7):969-970.
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