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Book

Wiskott-Aldrich Syndrome

Muhammad Ahmed Malik  1 , Muhammad Masab  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Wiskott-Aldrich Syndrome

Muhammad Ahmed Malik et al.
Free Books & Documents

Excerpt

Wiskott-Aldrich syndrome is a rare X-linked disorder with a characteristic triad of immunodeficiency, thrombocytopenia, and eczema. It results from a genetic mutation in the gene encoding Wiskott-Aldrich syndrome protein (WASp) affecting the immune system and inducing a state of immunodeficiency. The disease follows a broad spectrum depending on gene mutations ranging from severe phenotype (classic WAS) to milder ones (X-linked thrombocytopenia (XLT) and X-linked neutropenia).

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Conflict of interest statement

Disclosure: Muhammad Ahmed Malik declares no relevant financial relationships with ineligible companies.

Disclosure: Muhammad Masab declares no relevant financial relationships with ineligible companies.

References

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