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Book

Physiology, Neurotransmitters

Zachary M. Sheffler  1 , Vamsi Reddy  2 , Leela Sharath Pillarisetty  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Physiology, Neurotransmitters

Zachary M. Sheffler et al.
Free Books & Documents

Excerpt

Neurotransmitters are endogenous chemicals that allow neurons to communicate with each other throughout the body. They enable the brain to provide a variety of functions, through the process of chemical synaptic transmission. These endogenous chemicals are integral in shaping everyday life and functions.

Chemical synaptic transmission primarily through the release of neurotransmitters from presynaptic neural cells to postsynaptic receptors. Alterations in the levels of specific neurotransmitters have been observed in various neurological disorders, including Parkinson disease, schizophrenia, depression, and Alzheimer disease.

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Conflict of interest statement

Disclosure: Zachary Sheffler declares no relevant financial relationships with ineligible companies.

Disclosure: Vamsi Reddy declares no relevant financial relationships with ineligible companies.

Disclosure: Leela Sharath Pillarisetty declares no relevant financial relationships with ineligible companies.

References

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    1. Herlenius E, Lagercrantz H. Neurotransmitters and neuromodulators during early human development. Early Hum Dev. 2001 Oct;65(1):21-37. - PubMed
    1. Herlenius E, Lagercrantz H. Development of neurotransmitter systems during critical periods. Exp Neurol. 2004 Nov;190 Suppl 1:S8-21. - PubMed
    1. Zhou Y, Danbolt NC. Glutamate as a neurotransmitter in the healthy brain. J Neural Transm (Vienna) 2014 Aug;121(8):799-817. - PMC - PubMed
    1. Gross L. "Supporting" players take the lead in protecting the overstimulated brain. PLoS Biol. 2006 Nov;4(11):e371. - PMC - PubMed

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