Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Oseltamivir

Moushumi Sur  1 , Michael J. Lopez  2 , Preeti Patel, Mari B. Baker  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Oseltamivir

Moushumi Sur et al.
Free Books & Documents

Excerpt

Oseltamivir is an antiviral medication used to manage acute, uncomplicated influenza A or B in adult and pediatric patients, including neonates older than 2 weeks. For neonates younger than 2 weeks, using oseltamivir to treat influenza is considered, although the safety and efficacy in this population remain unestablished. National advisory bodies advocate the initiation of oseltamivir within 48 hours of symptom onset, particularly for individuals hospitalized with influenza or possessing significant comorbidities placing them at heightened risk for complications. This activity explores oseltamivir's indications, mechanism of action, administration protocols, significant adverse effects, contraindications, monitoring strategies, and potential toxicity. The goal is to equip healthcare providers with the necessary knowledge to guide patient therapy effectively, ultimately optimizing outcomes in the combat against influenza and related viral infections.

PubMed Disclaimer

Conflict of interest statement

Disclosure: Moushumi Sur declares no relevant financial relationships with ineligible companies.

Disclosure: Michael Lopez declares no relevant financial relationships with ineligible companies.

Disclosure: Preeti Patel declares no relevant financial relationships with ineligible companies.

Disclosure: Mari Baker declares no relevant financial relationships with ineligible companies.

References

    1. Cooper NJ, Sutton AJ, Abrams KR, Wailoo A, Turner D, Nicholson KG. Effectiveness of neuraminidase inhibitors in treatment and prevention of influenza A and B: systematic review and meta-analyses of randomised controlled trials. BMJ. 2003 Jun 07;326(7401):1235. - PMC - PubMed
    1. COMMITTEE ON INFECTIOUS DISEASES. Recommendations for Prevention and Control of Influenza in Children, 2017 - 2018. Pediatrics. 2017 Oct;140(4) - PubMed
    1. COMMITTEE ON INFECTIOUS DISEASES. Recommendations for Prevention and Control of Influenza in Children, 2021-2022. Pediatrics. 2021 Oct;148(4) - PubMed
    1. Fiore AE, Fry A, Shay D, Gubareva L, Bresee JS, Uyeki TM, Centers for Disease Control and Prevention (CDC) Antiviral agents for the treatment and chemoprophylaxis of influenza --- recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2011 Jan 21;60(1):1-24. - PubMed
    1. Harper SA, Bradley JS, Englund JA, File TM, Gravenstein S, Hayden FG, McGeer AJ, Neuzil KM, Pavia AT, Tapper ML, Uyeki TM, Zimmerman RK, Expert Panel of the Infectious Diseases Society of America Seasonal influenza in adults and children--diagnosis, treatment, chemoprophylaxis, and institutional outbreak management: clinical practice guidelines of the Infectious Diseases Society of America. Clin Infect Dis. 2009 Apr 15;48(8):1003-32. - PMC - PubMed

Publication types

LinkOut - more resources