Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Jun;112(6):769-774.
doi: 10.5935/abc.20190070. Epub 2019 Apr 8.

Surgical Site Infection Prevention Bundle in Cardiac Surgery

[Article in English, Portuguese]
Affiliations

Surgical Site Infection Prevention Bundle in Cardiac Surgery

[Article in English, Portuguese]
Lilian Silva de Andrade et al. Arq Bras Cardiol. 2019 Jun.

Abstract

Background: Surgical site infections (SSI) are among the most prevalent infections in healthcare institutions, attributing a risk of death which varies from 33% to 77% and a 2- to 11-fold increase in risk of death. Patients submitted to cardiac surgery are more susceptible to SSI, accounting for 3.5% to 21% of SSI. The mortality rate attributable to these causes is as high as 25%. Prevention of SSI in cardiac surgery is based on a bundle of preventive measures, which focus on modifiable risks.

Objective: The objective of this study was to identify SSI risk factors in clean cardiac surgery.

Methods: A retrospective cohort study analyzed 1,846 medical records from patients who underwent clean cardiac surgery. Fisher's exact test was used for bivariate comparison, and Poisson regression was used for independent analysis of SSI risk, considering a significance level of p < 0.05.

Results: The results of the study comprised a multivariate analysis. The variables that were associated with the diagnosis of SSI were: surgical risk index (OR: 2.575; CI: 1.224-5.416), obesity (OR: 2.068; CI: 1.457-2.936), diabetes mellitus (OR: 1,678; CI: 1.168-2.409), and blood glucose level (OR: 1.004; CI: 1.001-1.007).

Conclusions: This study evidenced that complete adherence to the bundle was not associated with a reduction in the risk of surgical infections. Diabetes mellitus, obesity, and surgical risk index assessment were, however, identified to increase association and consequently risk of SSI in cardiac surgery.

PubMed Disclaimer

Conflict of interest statement

Potential Conflict of Interest

No potential conflict of interest relevant to this article was reported.

References

    1. Allegranzi B. Report on the load associated infections endemic health care worldwide. Genebra: WHO; 2011.
    1. Horan TC, Andrus M, Dudeck MA. CDC surveillance definition / NHSN infections associated with health care and criteria for specific types of infections in the intensive care setting. Am J Infect Control. 2008;36(5):309–332. - PubMed
    1. World Health Organization Global Guidelines for the Prevention of Surgical Site Infection. [2018 Feb 23]. (WHO) Available from: www.who.int.
    1. Surveillance of surgical site infections in Europe 2010-2011. Stockholm: European Centre for Disease Prevention and Control; 2013. [2018 Aug 21]. Available from: ( https://ecdc.europa.eu/sites/portal/files/media/en/publications/Publicat....
    1. Le Guillou V, Tavolacci MP, Baste JM, Hubscher C, Bedoit E, Bessou JP, et al. Surgical site infection after central venous catheter related infection in cardiac surgery. Analysis of a cohort of 7557 patients. J Hosp Infect. 2011;79(3):236–241. - PubMed