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Review
. 2019 Mar 27:10:594.
doi: 10.3389/fimmu.2019.00594. eCollection 2019.

Advances in mRNA Vaccines for Infectious Diseases

Cuiling Zhang  1 , Giulietta Maruggi  2 , Hu Shan  1 , Junwei Li  1
Affiliations
Review

Advances in mRNA Vaccines for Infectious Diseases

Cuiling Zhang et al. Front Immunol. .

Abstract

During the last two decades, there has been broad interest in RNA-based technologies for the development of prophylactic and therapeutic vaccines. Preclinical and clinical trials have shown that mRNA vaccines provide a safe and long-lasting immune response in animal models and humans. In this review, we summarize current research progress on mRNA vaccines, which have the potential to be quick-manufactured and to become powerful tools against infectious disease and we highlight the bright future of their design and applications.

Keywords: application; delivery; infectious disease; mRNA vaccine; mechanism.

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Figures

Figure 1
Figure 1
The mechanisms of different nucleic acid vaccines, including DNA vaccines, mRNA vaccines. MHC, Major histocompatibility complex.
See this image and copyright information in PMC

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