Tracheal tumors
- PMID: 30973357
- DOI: 10.1097/MCP.0000000000000585
Tracheal tumors
Abstract
Purpose of review: This article provides the most recent literature and experienced guidance about diagnosis and management of tracheal tumors, including future directions.
Recent findings: Tracheal tumors are challenging to diagnose given their nonspecific and late-onset symptoms. Critical airway obstruction is the most feared complication. The cornerstone in management of them is surgical resection whenever is possible. Different diagnostic tests (i.e., imaging and bronchoscopy) help in the assessment of resectability. Alternative management including interventional bronchoscopic techniques can be offered to patients who are not suitable for surgical resection. Radiation and chemotherapy can also be used as adjuvant, neoadjuvant or sole treatment in malignant tumors. Recent advances in tracheal transplantation and bioengineering with tracheal reconstruction have shown a new direction in the management of these tumors. All these topics will be discussed in this article.
Summary: Despite advances in diagnostic and therapeutic techniques, tracheal tumors are still a medical challenge. Although studies are still trying to find the best surgical techniques as well as the role for chemotherapy and radiation, most recent studies are addressing tracheal reconstruction and transplantation as the new horizon for management.
Similar articles
-
Malignant tracheal tumors: a review of current diagnostic and management strategies.Curr Opin Pulm Med. 2015 Jul;21(4):322-6. doi: 10.1097/MCP.0000000000000181. Curr Opin Pulm Med. 2015. PMID: 25978628 Review.
-
Management of Primary Tracheal Tumors.Thorac Surg Clin. 2025 Feb;35(1):83-90. doi: 10.1016/j.thorsurg.2024.09.008. Epub 2024 Oct 18. Thorac Surg Clin. 2025. PMID: 39515898 Review.
-
Primary tracheal tumors.Chest Surg Clin N Am. 2003 May;13(2):247-56. doi: 10.1016/s1052-3359(03)00019-x. Chest Surg Clin N Am. 2003. PMID: 12755311 Review.
-
Management of malignant tracheobronchial obstruction.Surg Clin North Am. 2002 Jun;82(3):621-42. doi: 10.1016/s0039-6109(02)00025-7. Surg Clin North Am. 2002. PMID: 12371589 Review.
-
[Sequential approach in a case of tracheal hemangioma: segmental tracheal resection after Nd-YAG laser application].Pneumologia. 2005 Oct-Dec;54(4):191-4. Pneumologia. 2005. PMID: 17069223 Romanian.
Cited by
-
Role of radiation alone vs. concurrent chemoradiotherapy in surgically ineligible patients with tracheobronchial squamous cell carcinoma.J Thorac Dis. 2025 Mar 31;17(3):1312-1322. doi: 10.21037/jtd-24-1911. Epub 2025 Mar 27. J Thorac Dis. 2025. PMID: 40223947 Free PMC article.
-
Tracheostomy and venovenous extracorporeal membrane oxygenation for difficult airway patient with carinal melanoma: A case report and literature review.World J Clin Cases. 2022 Dec 16;10(35):13088-13098. doi: 10.12998/wjcc.v10.i35.13088. World J Clin Cases. 2022. PMID: 36569026 Free PMC article.
-
Primary tracheal meningiomas treated with endoscopy: a case description.Quant Imaging Med Surg. 2025 Sep 1;15(9):8684-8687. doi: 10.21037/qims-2025-879. Epub 2025 Aug 13. Quant Imaging Med Surg. 2025. PMID: 40893568 Free PMC article. No abstract available.
-
Clinical features and prognosis analysis of 57 patients with primary tracheal tumors.Transl Cancer Res. 2020 Feb;9(2):613-619. doi: 10.21037/tcr.2019.11.55. Transl Cancer Res. 2020. PMID: 35117406 Free PMC article.
-
Successful Resection of a Primary Dedifferentiated Tracheal Liposarcoma Causing Tracheal Stenosis.Intern Med. 2022 Mar 1;61(5):719-722. doi: 10.2169/internalmedicine.6696-20. Epub 2021 Aug 31. Intern Med. 2022. PMID: 34471016 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Research Materials