Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Guideline
. 2019 May;33(3):1127-1140.
doi: 10.1111/jvim.15488. Epub 2019 Apr 11.

ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs

Affiliations
Guideline

ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs

Bruce W Keene et al. J Vet Intern Med. 2019 May.

Abstract

This report, issued by the ACVIM Specialty of Cardiology consensus panel, revises guidelines for the diagnosis and treatment of myxomatous mitral valve disease (MMVD, also known as endocardiosis and degenerative or chronic valvular heart disease) in dogs, originally published in 2009. Updates were made to diagnostic, as well as medical, surgical, and dietary treatment recommendations. The strength of these recommendations was based on both the quantity and quality of available evidence supporting diagnostic and therapeutic decisions. Management of MMVD before the onset of clinical signs of heart failure has changed substantially compared with the 2009 guidelines, and new strategies to diagnose and treat advanced heart failure and pulmonary hypertension are reviewed.

Keywords: canine; congestive heart failure; evidence-based treatment; mitral.

PubMed Disclaimer

Conflict of interest statement

Bruce W. Keene—Consulted for Boehringer Ingelheim and CEVA Animal Health.

Clarke E. Atkins—Consulted for Boehringer Ingelheim and CEVA Animal Health.

John D. Bonagura —Consulted for Boehringer Ingelheim, IDEXX and CEVA Animal Health.

Philip R. Fox—Consulted for Boehringer Ingelheim, IDEXX and CEVA Animal Health.

Jens Häggström—Consulted for Boehringer Ingelheim, IDEXX and CEVA Animal Health.

Virginia Luis Fuentes—Consulted for Boehringer Ingelheim and CEVA Animal Health.

Mark A. Oyama—Consulted for Boehringer Ingelheim, CEVA Animal Health, and IDEXX.

John E. Rush—Consulted for Boehringer Ingelheim and IDEXX.

Rebecca Stepien—Consulted for Boehringer Ingelheim and IDEXX.

Masami Uechi—Consulted for Boehringer Ingelheim and TERUMO Corporation.

Figures

Figure 1
Figure 1
One of the 4 criteria that identify advanced Stage B2 in dogs is that the echocardiographic LA : Ao ratio as measured in the right‐sided short‐axis view in early diastole is ≥1.6. The measurement is illustrated. The blue arrow illustrates the measurement of the aortic dimension at the level of the aortic valve, and the orange arrow illustrates measurement of the left atrial dimension

References

    1. Yancy CW, Jessup M, Bozkurt B, et al. 2017 ACC/AHA/HFSA focused update of the 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association task force on clinical practice guidelines and the Heart Failure Society of America. J Am Coll Cardiol. 2017;70:776‐803. - PubMed
    1. Boller M, Fletcher DJ. RECOVER evidence and knowledge gap analysis on veterinary CPR. Part 1: evidence analysis and consensus process: collaborative path toward small animal CPR guidelines. J Vet Emerg Crit Care. 2012;22(Suppl.1):S4‐S12. - PubMed
    1. Fox PR. Pathology of myxomatous mitral valve disease in the dog. J Vet Cardiol. 2012;14:103‐126. - PubMed
    1. Meurs KM, Friedenberg SG, Williams B, et al. Evaluation of genes associated with human myxomatous mitral valve disease in dogs with familial myxomatous mitral valve degeneration. Vet J. 2018;232:16‐19. - PubMed
    1. Madsen MB, Olsen LH, Häggström J, et al. Identification of 2 loci associated with development of myxomatous mitral valve disease in cavalier king charles spaniels. J Hered. 2011;102:S62‐S67. - PubMed

Publication types

MeSH terms