Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Apr 11;21(4):17.
doi: 10.1007/s11894-019-0681-x.

The Epidemiology of Hepatocellular Carcinoma in the USA

Hyun-Seok Kim  1 , Hashem B El-Serag  2   3
Affiliations
Review

The Epidemiology of Hepatocellular Carcinoma in the USA

Hyun-Seok Kim et al. Curr Gastroenterol Rep. .

Abstract

Purpose of review: To discuss current knowledge and recent findings regarding the epidemiology of hepatocellular carcinoma (HCC) in the USA.

Recent finding: The US incidence rate of HCC is increasing, although the pace may have somewhat slowed since 2010. In 2012, incidence rates of HCC in Hispanics surpassed those of Asians. The recent epidemiological changes in major risk factors for HCC include increasing hepatitis C virus post-sustained virologic response, suppressed hepatitis B virus on nucleoside analogues, and alcoholic and non-alcoholic fatty liver disease. Non-alcoholic fatty liver disease has the greatest proportion of the burden of the main risk factors for HCC in the USA, followed by alcoholic liver disease, and hepatitis C virus and hepatitis B virus infections. This review focuses on current knowledge regarding the recent epidemiological trends in HCC, with an emphasis on future directions.

Keywords: Epidemiology; Hepatocellular carcinoma; Prevention.

PubMed Disclaimer

References

    1. Am J Epidemiol. 2002 Feb 15;155(4):323-31 - PubMed
    1. Gastroenterology. 2003 Feb;124(2):327-34 - PubMed
    1. Am J Gastroenterol. 2003 Mar;98(3):679-90 - PubMed
    1. J Cancer Res Clin Oncol. 2004 Jul;130(7):417-22 - PubMed
    1. Gastroenterology. 2004 Apr;126(4):1005-14 - PubMed

MeSH terms

LinkOut - more resources