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. 2019 Mar-Apr;13(2):48-55.

Uropathogens and their antimicrobial resistance patterns: Relationship with urinary tract infections

Syed Suhail Ahmed  1 , Ali Shariq  1 , Abdulaziz Ajlan Alsalloom  1 , Ibrahim H Babikir  1 , Badr N Alhomoud  1
Affiliations

Uropathogens and their antimicrobial resistance patterns: Relationship with urinary tract infections

Syed Suhail Ahmed et al. Int J Health Sci (Qassim). 2019 Mar-Apr.

Abstract

Objectives: This study was performed to determine the prevalence of uropathogens causing urinary tract infections (UTIs) and to determine their pattern of antimicrobial resistance.

Methods: This study was conducted on 273 urine samples collected from outpatient departments (OPDs) of Qassim University affiliated hospitals. Fully automated VITEK 2 compact system was used in the identification and antimicrobial susceptibility testing of causative microorganisms.

Results: Of 273 urine samples, only 89 (32.6%) were found to show significant growth for UTI, and overall, drug resistance was found in 92% (n = 82/89) of samples, with most (80%) being resistant to at least two drugs. Antibiotic resistance was commonly observed in ampicillin (88.3%), piperacillin (72.7%), clindamycin (66.7%), amoxicillin/clavulanic acid (66.2%), and trimethoprim/sulfamethoxazole (50%). The commonly isolated microorganisms were Escherichia coli 24 (27%), Klebsiella pneumoniae 11 (12.4%), Proteus mirabilis 4 (4.5%), Pseudomonas aeruginosa 4 (4.5%), Enterobacter cloacae 5 (5.6%), Enterococcus faecalis 5 (5.6%), and Staphylococcus saprophyticus 3 (3.4%).

Conclusions: This research work has shown that patients with UTI in Qassim are at high risk of antibiotic resistance. The work also showed that multidrug-resistant bacteria can lead to momentous therapeutic problems in OPD patients.

Keywords: Antimicrobial resistance; Escherichia coli; Klebsiella; Pseudomonas aeruginosa; VITEK system; multidrug resistance; qassim; uropathogens.

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Figures

Figure 1
Figure 1
Frequency distribution of isolated microorganisms from patients with catheter-associated urinary tract infection
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