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Review
. 2019 Apr 2:8:363.
doi: 10.12688/f1000research.17778.1. eCollection 2019.

Emerging medical therapies for congenital adrenal hyperplasia

Phyllis W Speiser  1
Affiliations
Review

Emerging medical therapies for congenital adrenal hyperplasia

Phyllis W Speiser. F1000Res. .

Abstract

Congenital adrenal hyperplasia has traditionally been treated with daily oral doses of glucocorticoids and mineralocorticoid supplements. Such therapy does not precisely replicate the adrenal cortex's circadian pattern. As a consequence, patients are intermittently overtreated or undertreated leading to growth suppression in children, excess weight gain and altered metabolism. Several new treatments are on the horizon. This article will summarize some new potential therapies as adjuncts to, or replacement for, standard therapy.

Keywords: congenital adrenal hyperplasia; treatment.

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Conflict of interest statement

Competing interests: The author has served as a medical consultant to Neurocrine Biosciences, San Diego, CA and has been considered for participation in several planned clinical trials.

References

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    2. F1000 Recommendation

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