A case of bilateral Parry-Romberg syndrome successfully treated with hyaluronic acid filler augmentation
- PMID: 30985058
- DOI: 10.1111/jocd.12948
A case of bilateral Parry-Romberg syndrome successfully treated with hyaluronic acid filler augmentation
Abstract
Parry-Romberg syndrome is a rare acquired neurocutaneous disorder typically characterized by hemifacial atrophy. Few cases of bilateral facial involvement have been reported. We report a case of a 60-year-old female with a 20-year history of progressive bilateral facial atrophy. Although an initial diagnosis of acquired partial lipodystrophy was considered, a diagnosis of bilateral Parry-Romberg was favored for three main reasons: (a) lipoatrophy was confined to the face (b) imaging findings of enophthalmos and underlying white matter changes (c) laboratories showing absence of C3 nephritic factor and normal complement levels. The patient was treated with hyaluronic acid fillers with dramatic improvement in cosmetic appearance.
Keywords: Parry-Romberg; hyaluronic acid filler; lipoatrophy.
© 2019 Wiley Periodicals, Inc.
References
REFERENCES
-
- Tolkachjov SN, Patel NG, Tollefson MM. Progressive hemifacial atrophy: a review. Orphanet J Rare Dis. 2015;10(1):39.
-
- Vix J, Mathis S, Lacoste M, Guillevin R, Neau J-P. Neurological manifestations in Parry-Romberg syndrome: 2 case reports. Medicine. 2015;94(28):e1147.
-
- Miller M, Spencer M. Progressive hemifacial atrophy (Parry-Romberg disease). Am J Ophthalmol. 1996;121(1):108.
-
- Stone J. Parry-Romberg syndrome: a global survey of 205 patients using the internet. Neurology. 2003;61(5):674-676.
-
- Bellusci C, Liguori R, Pazzaglia A, Badiali L, Schiavi C, Campos EC. Bilateral Parry-Romberg syndrome associated with retinal vasculitis. Eur J Ophthalmol. 2003;13(9-10):803-806.
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