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Review
. 2019 Apr 2;16(7):1185.
doi: 10.3390/ijerph16071185.

Role of Emerging Environmental Risk Factors in Thyroid Cancer: A Brief Review

Maria Fiore  1 , Gea Oliveri Conti  2 , Rosario Caltabiano  3 , Antonino Buffone  4 , Pietro Zuccarello  5 , Livia Cormaci  6 , Matteo Angelo Cannizzaro  7 , Margherita Ferrante  8
Affiliations
Review

Role of Emerging Environmental Risk Factors in Thyroid Cancer: A Brief Review

Maria Fiore et al. Int J Environ Res Public Health. .

Abstract

Environmental factors are recognized as risk factors of thyroid cancer in humans. Exposure to radiation, both from nuclear weapon or fallout or medical radiation, and to some organic and inorganic chemical toxicants represent a worldwide public health issue for their proven carcinogenicity. Halogenated compounds, such as organochlorines and pesticides, are able to disrupt thyroid function. Polychlorinated biphenyls and their metabolites and polybrominated diethyl ethers bind to thyroid, transport proteins, replace thyroxin, and disrupt thyroid function as phthalates and bisphenolates do, highly mimicking thyroid hormones. A better knowledge of environmental risks represents a very important tool for cancer prevention through true risks prevention and management. This approach is very important because of the epigenetic origin's theory of cancer. Therefore, the aim of this review was study the association between environmental agents and thyroid cancer promotion.

Keywords: ECDs; cancer; carcinogenicity; environment; risk; thyroid; toxics.

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Conflict of interest statement

The authors declare no conflict of interest.

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