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Review
. 2018 Dec 14;12(5):125-129.
doi: 10.1002/cld.760. eCollection 2018 Nov.

Hepatitis C Virus Diagnostics: The Road to Simplification

Jordan J Feld  1
Affiliations
Review

Hepatitis C Virus Diagnostics: The Road to Simplification

Jordan J Feld. Clin Liver Dis (Hoboken). .
No abstract available

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Figures

Figure 1
Figure 1
Cascade with drop‐off to HCV RNA. As shown, one of the largest drop‐offs in the cascade of care occurs after HCV antibody testing. Many patients never receive an HCV RNA test to determine whether they have active infection and require therapy. Reprinted with permission from Mera et al. 2016.3
Figure 2
Figure 2
Steps in current algorithm for HCV diagnosis. Each of the multiple steps, from initial testing to a confirmed diagnosis of chronic HCV infection, leave the potential for loss to follow‐up (F/U).
Figure 3
Figure 3
DBS testing allows for sequential testing to occur. Whole blood is taken from a fingerprick, meaning venipuncture is not required. After drying, the card can be sent to the central laboratory for testing. The first spot can be tested for HCV antibody, and if positive, subsequent spots can be tested for HCV RNA, HCV genotype, and other infections.
See this image and copyright information in PMC

References

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